Reiki is the most studied biofield therapy. Mikao Usui developed the system in 1920s Japan. The protocol involves the practitioner placing hands lightly on or just above the recipient's body in a sequence of standard positions for 60 to 90 minutes. The recipient typically lies fully clothed on a treatment table.

The 2025 scoping review of biofield therapies in the Journal of Integrative and Complementary Medicine identified 353 studies, with Reiki representing the largest sub-corpus. The 2017 McManus systematic review concluded Reiki produces effects beyond placebo on pain, anxiety, depression, and self-esteem outcomes. The 2024 BMC Palliative Care meta-analysis covered 13 Reiki studies and 824 patients, finding significant impact on anxiety, particularly for short-term protocols of 1 to 3 sessions.

Major hospitals including Cleveland Clinic, OHSU, Yale, Memorial Sloan Kettering, and Johns Hopkins offer Reiki through integrative medicine programmes. Clinical adoption sits ahead of definitive proof, reflecting moderate reliable benefit at low cost and minimal risk.

Mechanism: the autonomic regulation hypothesis. Reiki sessions produce measurable cortisol reduction, decreased respiration rate, and lower systolic blood pressure. The 2017 Baldwin pilot at Cleveland Clinic showed real-Reiki recipients had respiration drop that sham-Reiki controls did not match.

Best evidence-based fit: pre-procedural anxiety, post-surgical recovery, fibromyalgia, chronic-condition anxiety, cancer-related fatigue. Weakest fit: severe mental illness as primary treatment, structural disease.

References

  • 2025 JICM Scoping Review
  • 2024 BMC Palliative Care Meta-Analysis
  • 2017 McManus SAGE Systematic Review
  • 2017 Baldwin Cleveland Clinic Pilot

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